Systemic hemodynamic effects of norepinephrine versus phenylephrine in intermittent bolus doses during spinal anesthesia for cesarean delivery
نویسندگان
چکیده
منابع مشابه
Comparison of prophylactic bolus norepinephrine and phenylephrine on hypotension during spinal anesthesia for cesarean section
Background and objective: Phenylephrine is the first-line choice for prevention and treatment of hypotension during spinal anesthesia for cesarean section. However, the serious bradycardia caused by phenylephrine is a concern. This study compared the effects of prophylactic bolus norepinephrine and phenylephrine on hypotension during spinal anesthesia for cesarean section. Methods: A total of 1...
متن کاملFetal and maternal effects of phenylephrine and ephedrine during spinal anesthesia for cesarean delivery.
BACKGROUND In our routine practice, we observed a reduced incidence of fetal acidosis (umbilical artery pH < 7.20) at cesarean delivery during spinal anesthesia when a combination of phenylephrine and ephedrine was used as first line vasopressor therapy, compared with using ephedrine alone. METHODS The study was randomized and double blind. It compared phenylephrine 100 microg/ml (phenylephri...
متن کاملPlacental transfer and fetal metabolic effects of phenylephrine and ephedrine during spinal anesthesia for cesarean delivery.
BACKGROUND Use of ephedrine in obstetric patients is associated with depression of fetal acid-base status. The authors hypothesized that the mechanism underlying this is transfer of ephedrine across the placenta and stimulation of metabolism in the fetus. METHODS A total of 104 women having elective Cesarean delivery under spinal anesthesia randomly received infusion of phenylephrine (100 mic...
متن کاملRandomized double-blinded comparison of norepinephrine and phenylephrine for maintenance of blood pressure during spinal anesthesia for cesarean delivery.
BACKGROUND During spinal anesthesia for cesarean delivery, phenylephrine can cause reflexive decreases in maternal heart rate and cardiac output. Norepinephrine has weak β-adrenergic receptor agonist activity in addition to potent α-adrenergic receptor activity and therefore may be suitable for maintaining blood pressure with less negative effects on heart rate and cardiac output compared with ...
متن کاملComparison of hemodynamic changes between phenylephrine and combined phenylephrine and glycopyrrolate groups after spinal anesthesia for cesarean delivery
BACKGROUND Hypotension remains a common clinical problem of spinal anesthesia for cesarean delivery and phenylephrine is used as a vasopressor to address this. However, phenylephrine reduces maternal cardiac output (CO) due to reflex bradycardia. Glycopyrrolate is safe for the fetus, and increases heart rate (HR). Using a noninvasive measure of CO, we compared maternal hemodynamic changes betwe...
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ژورنال
عنوان ژورنال: Anesthesia and Pain Medicine
سال: 2020
ISSN: 1975-5171,2383-7977
DOI: 10.17085/apm.2020.15.1.53